I own both and hunt with both. I happen to have both chambered in M77 Hawkeyes. The biggest difference between them for someone looking for a medium, to me, would be the availability of factory loads for those who do not handload. When I shoot my .338F with the 200gr Fusion load (2650 FPS) alongside a 30/06 with typical 180gr loads in like rifles, I see zero difference in recoil to my shoulder. I found this Fusion load to be very accurate (sub MOA) in my Hawkeye and also performs very well on game. The .338F is a much flatter shooting cartridge than the .358 shooting Winchester's factory offering. Move up to Double Tap or Buffalo Bore for the hot .358 loads and it will even out, but at a cost, $$$$.The Federal cartridge 338 Fed does have some buzz going at this time and is available in short action bolt rifles. I know Ruger M77 Hawkeyes and Sako/Tikka rifles are available in 338 Fed. Does anyone have actual experience with both cartridges that they can share their preference between them? What I read sounds very good but they do say Federal loaded them to where recoil is a factor.