Hi, from Montana, Bestman. I pretty much agree with the other guys. Although the 25/06 can easily kill any deer at any reasonable range, if you already have a .270, there's no reason I can think of to switch to a 25/06. The .270 has been around for a long time - Winchester introduced it in 1925 - and it is still going strong. Whatever you shoot, be sure to match the bullet weight and construction to the job at hand. Even the right "light" weight bullet can be incredibly effective if it has the right construction. The most popular weight for the .270 is the 130 grainer. That will drop any deer in it's tracks provided you hit it in the right place - which is the key to killing any animal no matter how big your bullet is or what caliber you are using.