Unless it kicks so much that the shooter is scared of it
We have all seen it, someone with a cannon on the firing line that wishes it didn't hurt so much with each pull of the trigger. That is why I am anti magnum, not that they aren't incredible. It is just that 99% of the shooters on the line would be better served with something from the standard list of cartridges(30-06 class). I have seen Deer hunters sighting in a 375 H&H. It was bought for bragging rights at Deer camp that year. The shooter was sure his buddy would top him with a 416 Rem next year.
Let's see a Deer weights ~200 lbs, an Elephant several thousand. I guess it would be funny watching the 416 shooter sight in for the years opener. I just hope they have plenty of eye relief from their scope.