Hunting Man and I are big 280 fans. I have killed more game with it than I can count - everything from small pronghorns to big bull elk - it's another round (like the 30/06) that does it all... but it is an overlooked caliber, to be sure. All of the other rounds mentioned are more than adequate for your needs. As for an all-weather rifle, which you said you wanted - take a look at a Tikka T3 Lite (stainless/synthetic). I bought one just to see if it were as good as everyone had said. It was! Guaranteed to shoot one inch groups at 100 yards. It does! And it is less expensive than most of the rifles mentioned, and comes with scope rings. Good luck.