RELOAD AT THE FIRST TACTICAL PAUSE.
If there is a time-out in the action, use it to reload. Although your gun may not be empty, reload anyway. All of your opponent's buddies may have heard all the activity and are headed your way. It would be nice to have a full gun.
BEFORE YOU QUIT THE FIGHT, MAKE SURE THE FIGHT'S OVER.
Back in the "old days" we used to tell Guards and Cops on the range, "fire two shots and re-holster your weapon". This is fine on the range ... until a couple of them did it on the street. Well, they didn't hit the bad guy with the first shots and "automatically" re-holstered, only to be shot by the bad guy! We also learned that people don't think in a highly stressful situation, they react ... so practice like its real life.