I have a hard time looking at my Colt trooper MK3 and seriously consider it a deer hunting rig. Maybe the old 41, but I'll stick to my opinion that the 357 should stay what it was created for, 2 legged upright walkers.
Yup, bought me a Ruger Blackhawk over 30 years ago for just that purpose - them two legged varmints. Still have the thing in my gun safe. Mama likes it too, even named it for me -- Sandy -- just don't ask me where she got the name for it. Ain't got a clue!
As for using it for deer? Nah! Got too many other toys that work a whole lot better.