I just bought the buckstalker myself, really liking it so far. It is true to its name and that .50 cal will drop a deer, loads vary from person to person as everyone seems to have that one perfect load. Find what works for you, you can fine tune your load outs with loose powder, its more hassle but probably gains maximum results.
Overall depending on the round you are shooting you can be pushing usually anywhere from a .45 to .50 cal 200+ grain round with some fairly impressive energy potential and decent muzzle velocity into a deer, using the proper rounds you can do some massive damage in there. Shot placement is king, all that is probably preaching to the choir if you love to play the strings.