The Handgun you're looking for is the Taurus "Judge" hands down.
The Judge chambers a .45 Colt OR 410 Shotshells.
It's ALSO available as a Magnum for the 3" .410 shotshells
Watch this JUDGE Video and you'll be convinced. It has great Reviews too.
Good Luck HM
Democracy is two wolves and a lamb voting on what to have for lunch.
Liberty is a well-armed lamb contesting the outcome of the vote.